U.S., June 18 -- ClinicalTrials.gov registry received information related to the study (NCT07652216) titled 'Bone Defects Reconstruction After Dentigerous Cyst Enucleation With Autogenous Demineralized Dentin Matrix- ADDM and Platelet Rich Fibrin- PRF.' on June 11.

Brief Summary: This prospective clinical study evaluates bone healing following dentigerous cyst enucleation associated with impacted mandibular third molar extraction. The study compares spontaneous blood clot healing, advanced platelet-rich fibrin (A-PRF), and A-PRF combined with allogenic dentin-derived matrix (ADDM). Bone healing is assessed as the primary outcome, while postoperative pain intensity assessed using the Numerical Rating Scale (NRS) with graphical representatio...