Clinical Trial: Bilateral Versus Unilateral Lymph Node Dissection in High-Risk Prostate Cancer (BALANCE)

U.S., May 13 -- ClinicalTrials.gov registry received information related to the study (NCT07580196) titled 'Bilateral Versus Unilateral Lymph Node Dissection in High-Risk Prostate Cancer (BALANCE)' on April 20.

Brief Summary: BALANCE is a multicenter, prospective, randomized controlled trial enrolling men with unilateral high-risk localized prostate cancer identified by prostate biopsy, multiparametric MRI, and PSMA PET imaging. Eligible patients scheduled for robot-assisted radical prostatectomy will be randomized in a 1:1 ratio to undergo either unilateral extended pelvic lymph node dissection or bilateral extended pelvic lymph node dissection.

Pelvic lymph node dissection is commonly performed in high-risk prostate cancer for staging p...