Clinical Trial: Assessing Molecular Mechanisms and Effects of Music Therapy in Youth With Sickle Cell Disease Using Single-cell RNA-sequencing

U.S., May 2 -- ClinicalTrials.gov registry received information related to the study (NCT07562451) titled 'Assessing Molecular Mechanisms and Effects of Music Therapy in Youth With Sickle Cell Disease Using Single-cell RNA-sequencing' on April 27.

Brief Summary: The goal of this clinical trial is to evaluate whether a 4-week music therapy (MT) intervention can reduce chronic pain and improve psychosocial outcomes in youth with sickle cell disease (SCD).

The main questions it aims to answer are:

* Does MT reduce pain intensity, frequency of pain episodes, and improve health-related quality of life (HRQoL)?

* Does MT alter immune cell composition and gene expression in inflammatory pathways, as measured by single-cell RNA sequencing (scRN...