Clinical Trial: Arginine-Restricted Diet Combined With Chemoradiotherapy in Neoadjuvant Rectal Cancer: A Phase Ib/II Trial

U.S., Nov. 4 -- ClinicalTrials.gov registry received information related to the study (NCT07912346) titled 'Arginine-Restricted Diet Combined With Chemoradiotherapy in Neoadjuvant Rectal Cancer: A Phase Ib/II Trial' on Oct. 27.

Brief Summary: This is a Phase Ib/II clinical trial designed to evaluate the safety, tolerability, and preliminary efficacy of an arginine-restricted diet combined with standard neoadjuvant chemoradiotherapy in patients with locally advanced middle/high rectal cancer.

Background: Standard neoadjuvant chemoradiotherapy is the standard treatment for locally advanced rectal cancer to shrink tumors before surgery. However, the rate of complete tumor disappearance (pathological complete response) with standard treatment...