U.S., Nov. 3 -- ClinicalTrials.gov registry received information related to the study (NCT07908342) titled 'Application of Perinatal Derivatives in Total Knee Arthroplasty' on Oct. 26.
Brief Summary: This pilot study investigators whether the use of perinatal derivatives during knee replacement, in the form of an injection around the joint and patch over the knee joint incision, improves patient outcomes (including survey-based measures, functional outcomes and wound healing). Perinatal derivatives are materials derived from donor placental tissue, including amnion, chorion and umbilical cord. The perinatal derivatives used in this study do not contain living cells.
Forty-eight patients aged 40 to 75 years undergoing knee replacement will...