U.S., March 7 -- ClinicalTrials.gov registry received information related to the study (NCT07454772) titled 'Antibiotics vs Corticosteroids in Treatment of Granulomatous Lobular Mastitis' on Nov. 17, 2025.
Brief Summary: The goal of this clinical trial is to find the most effective and safe medical treatment for Granulomatous Lobular Mastitis (GLM) - a rare, chronic inflammatory breast disease that affects young and middle-aged women, often following childbirth.
The main questions it aims to answer are:
Does an antibiotic regimen (clarithromycin, ofloxacin, rifaximin) lead to faster and complete healing (Complete Clinical Response) compared to steroids?
Do steroids (prednisolone in tapering doses) provide better symptom control or cause...