U.S., March 19 -- ClinicalTrials.gov registry received information related to the study (NCT07479719) titled 'Anesthesia Maintenance With Target-controlled Infusion of Propofol and Remifentanil at Fixed Ratio' on March 11.
Brief Summary: The impact of anesthesia depths on early postoperative neurocognitive complications after total intravenous anesthesia (TIVA) remains controversial. In some studies investigating TIVA, anesthesiologists mainly achieve the target depth of anesthesia by adjusting the dose of propofol, whereas the doses of opioids remains comparable between different anesthetic depth groups, possibly resulting inadequate analgesia. This study is aimed to investigate the impact of different anesthesia depths maintained by targ...