Clinical Trial: Alterations of the Renin-angiotensin-aldosterone System in sEptic Shock

U.S., July 24 -- ClinicalTrials.gov registry received information related to the study (NCT07721974) titled 'Alterations of the Renin-angiotensin-aldosterone System in sEptic Shock' on July 20.

Brief Summary: Septic shock is a common and life-threatening condition associated with an in-hospital mortality rate exceeding 40%. The symptomatic management of septic shock relies primarily on vasopressor therapy, particularly norepinephrine. However, the use of high doses of norepinephrine may lead to adverse effects, prompting the search for alternative therapeutic strategies, including angiotensin II, which has recently been investigated as an adjunctive vasopressor.

Indeed, alterations of the renin-angiotensin-aldosterone system (RAAS), parti...