U.S., Oct. 7 -- ClinicalTrials.gov registry received information related to the study (NCT07861867) titled 'AKG and Brain Health in Aging' on Sept. 25.
Brief Summary: This proposal will test the hypothesis that AKG supplementation will improve NGVC responses and cognitive performance in older adults. We will also test the hypothesis that these effects are mediated by a decrease in age-related oxidative stress within NGVU cells.
Study Start Date: Feb. 01, 2027
Study Type: INTERVENTIONAL
Condition:
Brain Aging
Cerebrovascular Function
Intervention:
DIETARY_SUPPLEMENT: Calcium AKG
Participants will be randomized to receive either oral Calcium AKG at a total daily dose of 1 g or an identically appearing placebo for 24 weeks.
DIETARY_SU...