U.S., April 10 -- ClinicalTrials.gov registry received information related to the study (NCT07519408) titled 'Acute Kidney Injury and Ultra-endurance Running' on March 31.
Brief Summary: This study aims to understand how participating in the Western States Endurance Run (WSER), a 100-mile ultramarathon, affects kidney health. Long, strenuous exercise in hot conditions can temporarily strain the kidneys, especially when combined with dehydration, muscle breakdown, and the use of common pain-relief medications such as ibuprofen. Although kidney stress has been reported in endurance sports, no study has examined it directly in runners during the WSER using newer, more sensitive urine markers of kidney injury. Runners who volunteer will comple...