U.S., Oct. 10 -- ClinicalTrials.gov registry received information related to the study (NCT07214727) titled 'A Study to Evaluate ALN-5288 in Patients With Alzheimer's Disease' on Oct. 06.

Brief Summary: The purpose of this study is to:

* Evaluate the safety and tolerability of intrathecal (IT) ALN-5288 in patients with Alzheimer's Disease (AD)

* Evaluate the pharmacodynamic (PD) and pharmacokinetic (PK) effects of ALN-5288 after dose administration

Study Start Date: Oct. 09

Study Type: INTERVENTIONAL

Condition: Alzheimer's Disease

Intervention: DRUG: ALN-5288

ALN-5288 will be administered IT.

DRUG: Placebo

Placebo will be administered IT.

Recruitment Status: NOT_YET_RECRUITING

Sponsor: Alnylam Pharmaceuticals

Disclaimer: Cura...