Clinical Trial: A Phase IV Randomized Trial of Maxigesic(R) Versus Standard Analgesia After Radical Gastrectomy

U.S., July 8 -- ClinicalTrials.gov registry received information related to the study (NCT07687394) titled 'A Phase IV Randomized Trial of Maxigesic(R) Versus Standard Analgesia After Radical Gastrectomy' on June 18.

Brief Summary: Background: Radical gastrectomy causes moderate-to-severe pain during the first 48 hours after surgery. Opioids are effective but carry adverse effects and risks of prolonged use, so ERAS-based care recommends multimodal analgesia. Acetaminophen is the most commonly used non-opioid analgesic in gastrectomy patients; adding ibuprofen as a fixed-dose combination has shown improved analgesia and opioid-sparing effects compared with acetaminophen alone in other surgical populations, but direct evidence in gastrectom...