U.S., Oct. 20 -- ClinicalTrials.gov registry received information related to the study (NCT07881809) titled 'A Clinical Study of Ixazomib to Reactivate HIV and Reduce HIV Reservoir Size' on Oct. 13.
Brief Summary: This study tests whether a medicine called ixazomib is safe for people living with HIV, and whether it can wake up HIV that is hiding in the body so the immune system and treatment can reach it.
HIV can stay hidden inside cells even when antiretroviral therapy (ART) keeps the virus under control. These hidden cells are called the HIV reservoir, and they are the reason HIV is not cured by ART alone. Laboratory research suggests ixazomib may reactivate hidden HIV and also help kill the cells that carry it. Ixazomib is already appr...