Kanpur, Sept. 11 -- Researchers at the Indian Institute of Technology Kanpur have developed a novel antibody-based biosensor that can monitor the activation of G protein-coupled receptors (GPCRs) in live cells.
GPCRs are the largest family of receptor proteins in human cells and are targeted by more than one-third of all clinically prescribed medicines.
Led by Prof. Arun K. Shukla, the research team has been investigating GPCR biology for over a decade.
GPCRs, because of their central role, are considered some of the most important gateways for developing new drugs and therapies. The new biosensor represents a significant milestone in overcoming the technical challenges of monitoring receptor activation inside living cells.
GPCRs typica...