India, Nov. 4 -- Researchers at the UCLA Health Jonsson Comprehensive Cancer Center have found a possible way to make immune cells stronger and help them fight cancer for a longer time.
The study, published in Frontiers in Immunology, found that temporarily activating a protein called p53 helped immune cells develop better cancer-fighting abilities. The treated cells had more energy, showed fewer signs of exhaustion and were more effective at killing melanoma cells in laboratory tests.
In this research, the UCLA team studied p53, a protein that helps prevent cancer by stopping damaged cells from growing uncontrollably, which is often called the 'guardian of the genome'.
For the experiment, scientists collected human T cells and treated t...