New Delhi, May 13 -- Wall Street stock indices were mixed on Wednesday following report of a sharp spike in April inflation, coinciding with US President Donald Trump's arrival in Beijing for a high-stakes summit with Chinese leader Xi Jinping.

As of 10:45 a.m. Eastern Time, the S&P 500 was virtually unchanged, the Dow Jones Industrial Average was down 0.4%, and the Nasdaq Composite was 0.4% higher.

At 09:45 a.m. ET, the Dow Jones Industrial Average fell 249.05 points, or 0.50%, to 49,511.51, the S&P 500 lost 13.91 points, or 0.19%, to 7,387.05 and the Nasdaq Composite gained 3.40 points, or 0.01%, to 26,091.60.

About 15 minutes into trading, the Dow Jones Industrial Average was down 0.5% at 49,525.78. The broad-based S&P 500 slipped 0...