Japan Intellectual Property Rights: GUANINE-RICH OLIGONUCLEOTIDES

Japan, Sept. 16 -- KUROS US LLC has got intellectual property rights for 'GUANINE-RICH OLIGONUCLEOTIDES.' Other related details are as follows:

Application Number: JP,2023-185076

Category (FI): C07H21/00,C12N15/11@Z,C07H21/04@A

Stage: PROBLEM TO BE SOLVED: To provide methods for oligonucleotide synthesis, specifically the synthesis of oligonucleotides that contain a high content of guanine monomers.SOLUTION: A method for coupling a nucleoside phosphoramidite during the synthesis of an oligonucleotide to a universal support, to a first nucleoside, or to an extending oligonucleotide, wherein the oligonucleotide comprises a region of 3 or more consecutive guanine monomers, and wherein the method comprising the steps of: (i) generating a cou...