MUMBAI, India, July 24 -- Intellectual Property India has published a patent application (202647086175 A) filed by Idorsia Pharmaceuticals Ltd on July 14, 2026, for Macrocyclic Orexin Agonists.

Inventors include Bezencon, Olivier; Chevillard, Florent; Hell, Sandrine; Peters, Jens-Uwe; Pozzi, Davide; Siegrist, Romain Number; and Surivet, Jean-Philippe.

The application for the patent was published on July 17, 2026, under issue no. 29/2026.

Abstract: The present invention relates to aryl thiol macrocycles of Formula (I) wherein R1, R2, RA1, X1, X2, X3, X4, L, X5, and Ring A are as described in the description, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals. The invention also concerns related aspects inclu...