MUMBAI, India, Nov. 2 -- Intellectual Property India has published a patent application (202617094991 A) filed by Denali Therapeutics Inc. on August 05, 2026, for Compositions And Methods For Modulating Tau Expression.

Inventors include Devos, Sarah L.; Barker, Scarlett; Thayer, Mai B.; Nilewski, Lizanne G.; Osipov, Maksim; Klar, Richard; Michel, Sven; Jaschinski, Frank; and Rothkirch, Larissa.

The application for the patent was published on October 30, 2026, under issue no. 44/2026.

Abstract: Described are Microtubule-associated protein tau (MAPT) antisense oligonucleotides (ASOs) and MAPT ASO conjugates, and methods of using the MAPT ASOs and MAPT ASO conjugates to treat neurodegenerative disorders, such as Alzheimer's disease.

Discla...