Intellectual Property India Publishes Patent Application for Anti-Claudin18.2 Antibody-Camptothecin Drug Conjugate And Pharmaceutical Use Thereof

MUMBAI, India, July 13 -- Intellectual Property India has published a patent application (202617074809 A) filed by Systimmune, Inc. on June 17, 2026, for Anti-Claudin18.2 Antibody-Camptothecin Drug Conjugate And Pharmaceutical Use Thereof.

Inventors include Zhu, Yi; Zhuo, Shi; Wan, Weili; Zhang, Yong; and Li, Gangrui.

The application for the patent was published on July 10, 2026, under issue no. 28/2026.

Abstract: An antibody targeting human Claudin18.2 was coupled with a camptothecin analog to form a stable and homogeneous antibody-drug conjugate with a drug-to-antibody ratio (DAR) of 6.0-8.0. This antibody-drug conjugate has the structure shown in general formula I, where Ab refers to an antibody targeting Claudin18.2 coupled with a li...