MUMBAI, India, Nov. 2 -- Intellectual Property India has published a patent application (202541012821 A) filed by Neuland Laboratories Limited on February 14, 2025, for An Improved Process For The Preparation Of Ensifentrine.

Inventors include Dr. Narendra Kumar Tripathy; Dr. Mallam Venkataiah; Dr. Arupula Sanjeeva Kumar; Mr. Allu Srinivas; and Mr. Morthala Ramesh.

The application for the patent was published on October 30, 2026, under issue no. 44/2026.

Abstract: The present invention relates to an improved process for the preparation of Ensifentrine of Formula-I. which comprises: reacting of 1-(3,4-dimethoxyphenethyl)urea of Formula II with dimethylmalonate of Formula III to obtain 1-(3,4-dimethoxyphenethyl)pyrimidine-2,4,6(1H,3H,5H)-t...