Intellectual Property India Publishes Patent Application for Allele-Specific Knockdown Of Gene Expression

MUMBAI, India, Nov. 2 -- Intellectual Property India has published a patent application (202617093279 A) filed by University Of Massachusetts on July 31, 2026, for Allele-Specific Knockdown Of Gene Expression.

Inventors include Landers, John; and Powell, Desiree Marie.

The application for the patent was published on October 30, 2026, under issue no. 44/2026.

Abstract: Described herein are methods of inhibiting an allele that contains a mutation in a cell (e.g., treating a subject with an allele that contains a mutation). The method includes delivering to the cell an antisense oligonucleotide that targets a variant allele that is in cis with the mutation (e.g., the mutation is a gain of function mutation or a dominant negative mutation), ...