India, Feb. 28 -- Iran has shut down its airspace for civilian flights following joint "pre-emptive strikes" by Israel and the United States on Tehran, sharply escalating tensions in the region.

Speaking to IRNA, Iran's Civil Aviation Organization spokesperson Majid Akhavan said the airspace would remain closed for six hours.

Several missiles struck the University Street and Republic areas of Tehran. Iran's state-run IRNA reported thick smoke rising over parts of the city, with multiple explosions heard across the capital.

Media reports indicate that Iran's Supreme Leader Ali Khamenei has been relocated to a secure location following the attacks.

Calling the operation a "noble mission," Trump acknowledged the potential for casualties,...