India, Aug. 6 -- On Fortune's list of the 100 Most Powerful People in Business, a Mumbai-born woman rubs shoulders with the likes of Mark Zuckerberg and Mukesh Ambani. Reshma Kewalramani may not be as well known as her fellow Indian-origin executives like Sundar Pichai and Satya Nadella, but she has quietly made history as the first woman CEO to lead a major US biotechnology company.

Reshma Kewalramani is the Indian-origin CEO of Vertex Pharmaceuticals - a company valued at $110 billion. She is the first female CEO of a large US biotech company, having been appointed to the post in April 2020.

Kewalramani was born in Mumbai and moved to the US with her family when she was 11.

She started her career as a physician at Massachusetts Gener...