India, Feb. 20 -- Eric Dane, best known for playing Dr. Mark "McSteamy" Sloan on Grey's Anatomy, has died at 53 following a battle with ALS, his publicist confirmed.

A statement said he spent his final moments surrounded by loved ones and described his daughters as "the center of his world." Dane revealed in 2025 that he had amyotrophic lateral sclerosis (ALS), a progressive neurological disease, and later became an advocate for awareness and research.

Dane married actress Rebecca Gayheart in 2004. She filed for divorce in 2018 but later withdrew the petition.

In recent interviews, Gayheart said they had been separated for years while continuing to support one another as a family.

Speaking about navigating Dane's illness, she said she...