International Clinical Trial: Study on the safety and efficacy of citrate-containing replacement fluid in continuous renal replacement therapy for high-risk bleeding patients

Geneva, Jan. 12 -- International Clinical Trials Registry received information related to the study (ChiCTR2500115850) titled 'Study on the safety and efficacy of citrate-containing replacement fluid in continuous renal replacement therapy for high-risk bleeding patients' on Dec. 31, 2025.

Study Type: Interventional study

Study Design: Parallel

Primary Sponsor: Henan Provincial People's Hospita,medical

Condition: Critically ill patients requiring continuous renal replacement therapy

Intervention: 600 ml of Sodium Citrate Solution for Anticoagulation (200 ml: 8 g) + 4 L of Replacement Fluid for Standard CRRT (Citrate Concentration Approximately 18 mmol/L):600 ml of Sodium Citrate Solution for Anticoagulation + 4 L of replacement fl...