Geneva, Aug. 29 -- International Clinical Trials Registry received information related to the study (NCT07132242) titled 'SHR-A1811 Combine With Pyrotinib for Locally Advanced/Metastatic HER2 Positive Breast Cancer' on Aug. 1.

Study Type: Interventional

Study Design: Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Treatment. Masking: None (Open Label).

Primary Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Condition: Metastatic Breast Cancer With HER2 Positive

Intervention: Drug: SHR-A1811 4.0mg/kg Drug: Pyrotinib 240mg Drug: SHR-A1811 4.8mg/kg

Recruitment Status: Not recruiting

Phase: Phase 2

Date of First Enrollment: August 30, 2025

Target Sample Size: 84

To...