Geneva, Jan. 12 -- International Clinical Trials Registry received information related to the study (ChiCTR2500115154) titled 'Research on the Application of Tegileridine for Postoperative Analgesia in Elderly Patients after Total Knee Arthroplasty' on Dec. 23, 2025.

Study Type: Interventional study

Study Design: Parallel

Primary Sponsor: Lu'an Hospital of Anhui Medical University

Condition: Total knee arthroplasty

Intervention: Control Group (S Group, sufentanil 0.06 µg/kg·h + ondansetron 12mg + flurbiprofen ester 150mg + 0.9%NS,150ml in total):The group receive PCIA for postoperative analgesia after surgery, and set the dose of sufentanil in the PCIA formula to 0.06 µg/kg·h Low concentration group (T1 Group, ...