Geneva, Sept. 21 -- International Clinical Trials Registry received information related to the study (NCT07812493) titled 'Pirtobrutinib Plus Methotrexate-Based Chemoimmunotherapy for Systemic DLBCL With CNS Involvement' on Sept. 4.

Study Type: Interventional

Study Design: Allocation: N/A. Intervention model: Single Group Assignment. Primary purpose: Treatment. Masking: None (Open Label).

Primary Sponsor: Pengpeng Xu

Condition: Pirtobrutinib Immunochemotherapy DLBCL - Diffuse Large B Cell Lymphoma CNS Involvement of Systemic Lymphoma

Intervention: Drug: pirtobrutinib+MTX+immunolchemotherapy

Recruitment Status: Not recruiting

Phase: Phase 2

Date of First Enrollment: September 1, 2026

Target Sample Size: 24

Countries of Rec...