International Clinical Trial: Phase I Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetic Characteristics of GPN00068 Injection Following Single and Multiple Intravenous Doses in Healthy Subjects

Geneva, Jan. 12 -- International Clinical Trials Registry received information related to the study (ChiCTR2500114954) titled 'Phase I Clinical Trial to Evaluate the Safety, Tolerability, and Pharmacokinetic Characteristics of GPN00068 Injection Following Single and Multiple Intravenous Doses in Healthy Subjects' on Dec. 19, 2025.

Study Type: Interventional study

Study Design: Parallel

Primary Sponsor: Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

Condition: Sepsis

Intervention: Single dose increasing group:Single intravenous administration of GPN00068.

Low doses: 0.01 mg/kg, 0.04 mg/kg Administration: GPN00068 injection administered by intravenous bolus injection (within 30 seconds), sin...