International Clinical Trial: Optimal Programmed Intermittent Epidural Bolus Volume for Labor Analgesia with 0.1% Ropivacaine and 0.3 µg/ml Dexmedetomidine with Dural Puncture Epidural Technique: A Biased-Coin Up-and-Down Sequential Allocation Study

Geneva, March 20 -- International Clinical Trials Registry received information related to the study (ChiCTR2600119445) titled 'Optimal Programmed Intermittent Epidural Bolus Volume for Labor Analgesia with 0.1% Ropivacaine and 0.3 µg/ml Dexmedetomidine with Dural Puncture Epidural Technique: A Biased-Coin Up-and-Down Sequential Allocation Study' on Feb. 27.

Study Type: Interventional study

Study Design: Biased Coin Design

Primary Sponsor: Women and Children's Hospital, Qingdao University, Qingdao

Condition: Labor Analgesia

Intervention: Sequential experimental group:The biased coin design (BCD) was adopted to explore the effective dose, with dose adjustments performed at 8, 9, 10, 11, 12 and 13 mL. Each parturient started wi...