International Clinical Trial: Optimal Interval for Periodic Alveolar Recruitment Maneuvers Achieving 90% Lung Re-expansion During Intraoperative Mechanical Ventilation: A Randomized Biased-Coin Sequential Trial

Geneva, Jan. 12 -- International Clinical Trials Registry received information related to the study (ChiCTR2500114746) titled 'Optimal Interval for Periodic Alveolar Recruitment Maneuvers Achieving 90% Lung Re-expansion During Intraoperative Mechanical Ventilation: A Randomized Biased-Coin Sequential Trial' on Dec. 17, 2025.

Study Type: Interventional study

Study Design: Biased Coin Design

Primary Sponsor: The Sixth Affiliated Hospital, Sun Yat-sen University

Condition: atelectasis,lung-protective ventilation

Intervention: Experimental group:The initial time interval of PARM was 0.5 hours/time, and the different interval of PARM was assigned by random partial coin sequential method.If the previous patient did not respond to postop...