International Clinical Trial: Longitudinal Changes in the Vaginal Microbiome During Endocrine Therapy in Premenopausal Breast Cancer and Their Association with Genitourinary Syndrome of Menopause (GSM): A Single-Center Prospective Cohort Study

Geneva, Jan. 12 -- International Clinical Trials Registry received information related to the study (ChiCTR2500115283) titled 'Longitudinal Changes in the Vaginal Microbiome During Endocrine Therapy in Premenopausal Breast Cancer and Their Association with Genitourinary Syndrome of Menopause (GSM): A Single-Center Prospective Cohort Study' on Dec. 24, 2025.

Study Type: Observational study

Study Design: Cohort study

Primary Sponsor: Women's Hospital School of Medicine Zhejiang University

Condition: Breast cancer

Intervention: OFS plus aromatase inhibitor (OFS+AI) group:None

Recruitment Status: Not Recruiting

Phase: 0

Date of First Enrollment: 2026-01-01

Target Sample Size: OFS plus aromatase inhibitor (OFS+AI) group:55;OFS p...