International Clinical Trial: Investigating the inhibitory effect of 4-octyl itaconate on Th17 cell differentiation in human peripheral blood mononuclear cells provides a theoretical basis for its potential translation into a clinical therapeutic for dry eye disease

Geneva, April 20 -- International Clinical Trials Registry received information related to the study (ChiCTR2600121612) titled 'Investigating the inhibitory effect of 4-octyl itaconate on Th17 cell differentiation in human peripheral blood mononuclear cells provides a theoretical basis for its potential translation into a clinical therapeutic for dry eye disease' on April 1.

Study Type: Observational study

Study Design: Cohort study

Primary Sponsor: Tianjin Medical University Eye Hospital

Condition: Autoimmune dry eye disease

Intervention: Vehicle group and 4-OI group:None

Recruitment Status: Recruiting

Phase: N/A

Date of First Enrollment: 2026-04-01

Target Sample Size: Vehicle group and 4-OI group:10;4-OI group:10;

Count...