Geneva, Aug. 29 -- International Clinical Trials Registry received information related to the study (JPRN-UMIN000058722) titled 'Impact of increased blood flow in the retinal arteriole on vascular function' on Aug. 7.

Study Type: Interventional

Study Design: Cross-over Randomized

Primary Sponsor: Kitasato University

Condition: healthy adult males

Intervention: rest hypercapnia (5%CO2 + 21%O2 + N2 balance)-> (washout)-> handgrip exercise (30% of maximal voluntary contraction)-> (washout)-> warming the periocular area (45 degrees Celsius) rest-> warming the periocular area (45 degrees Celsius)-> (washout)-> hypercapnia(5%CO2 + 21%O2 + N2 balance)-> (washout)-> handgrip exercise (30% of maximal voluntary contraction...