Geneva, March 23 -- International Clinical Trials Registry received information related to the study (NCT07459673) titled 'HERizon-Breast: A ctDNA-Guided Adaptive Study of Sequential Anti-HER2 Therapies and CNS Prophylaxis to Induce Long-Term Remission' on March 5.

Study Type: Interventional

Study Design: Allocation: N/A. Intervention model: Single Group Assignment. Primary purpose: Treatment. Masking: None (Open Label).

Primary Sponsor: Memorial Sloan Kettering Cancer Center

Condition: Breast Cancer HER2-positive Breast Cancer Breast Cancer Stage IV

Intervention: Diagnostic Test: Personalis NeXT Personal Diagnostic Test: Natera Signatera

Recruitment Status: Recruiting

Phase: Phase 2

Date of First Enrollment: March 4, 2026 ...