International Clinical Trial: Gradient Hyperfractionation Compared With Conventional Fractionation Combined With Concurrent Chemoradiotherapy for Locally Advanced Nasopharyngeal Carcinoma That Has Not Achieved Remission After Neoadjuvant Chemoimmunotherapy: a Phase II Clinical Trial

Geneva, Jan. 12 -- International Clinical Trials Registry received information related to the study (ChiCTR2500115847) titled 'Gradient Hyperfractionation Compared With Conventional Fractionation Combined With Concurrent Chemoradiotherapy for Locally Advanced Nasopharyngeal Carcinoma That Has Not Achieved Remission After Neoadjuvant Chemoimmunotherapy: a Phase II Clinical Trial' on Dec. 31, 2025.

Study Type: Interventional study

Study Design: Parallel

Primary Sponsor: Fifth Affiliated Hospital, Sun Yat-Sen University

Condition: Patients with locally advanced nasopharyngeal carcinoma who did not respond (assessed as SD/PD by imaging) to immunotherapy combined with platinum-based chemotherapy

Intervention: Experimental group:Gradien...