Geneva, Jan. 12 -- International Clinical Trials Registry received information related to the study (NCT07301268) titled 'GI-102 Alone or in Combination With Pembrolizumab Before Surgery for the Treatment of Recurrent or Progressive IDH Wildtype Glioblastoma and IDH Mutated Grade 4 Astrocytoma' on Dec. 22, 2025.

Study Type: Interventional

Study Design: Allocation: Randomized. Intervention model: Parallel Assignment. Primary purpose: Treatment. Masking: None (Open Label).

Primary Sponsor: Mayo Clinic

Condition: Glioblastoma, IDH-Wildtype Progressive Astrocytoma, IDH-Mutant, Grade 4 Progressive Glioblastoma Progressive Gliosarcoma Recurrent Astrocytoma, IDH-Mutant, Grade 4 Recurrent Glioblastoma, IDH-Wildtype Recurrent Gliosarcoma Res...