International Clinical Trial: Extension Study of the PUMCH-E101 Clinical Trial: An open-label, single-center, single-dose study evaluating the safety, tolerability, and efficacy of intravitreal injection of PUMCH-E101 in patients with hereditary retinal diseases associated with RDH12 gene mutations in the contralateral eye

Geneva, Jan. 12 -- International Clinical Trials Registry received information related to the study (ChiCTR2500114927) titled 'Extension Study of the PUMCH-E101 Clinical Trial: An open-label, single-center, single-dose study evaluating the safety, tolerability, and efficacy of intravitreal injection of PUMCH-E101 in patients with hereditary retinal diseases associated with RDH12 gene mutations in the contralateral eye' on Dec. 19, 2025.

Study Type: Interventional study

Study Design: Single arm

Primary Sponsor: Chinese Academy of Medical Sciences, Peking Union Medical College Hospital

Condition: RDH12-associated inherited retinal diseases

Recruitment Status: Not Recruiting

Phase: N/A

Date of First Enrollment: 2025-12-24

Target...