International Clinical Trial: Effect of Bitopertin on the Liver and on Levels of Protoporphyrin IX in Bile, Blood, Liver, and Stool in Patients With Erythropoietic Protoporphyria/X-linked Protoporphyria and Increased Liver Stiffness and/or Liver Enzymes at Baseline

Geneva, Aug. 29 -- International Clinical Trials Registry received information related to the study (NCT07123363) titled 'Effect of Bitopertin on the Liver and on Levels of Protoporphyrin IX in Bile, Blood, Liver, and Stool in Patients With Erythropoietic Protoporphyria/X-linked Protoporphyria and Increased Liver Stiffness and/or Liver Enzymes at Baseline' on Aug. 7.

Study Type: Interventional

Study Design: Allocation: N/A. Intervention model: Single Group Assignment. Primary purpose: Treatment. Masking: None (Open Label).

Primary Sponsor: Wake Forest University Health Sciences

Condition: Protoporphyria

Intervention: Drug: bitopertin

Recruitment Status: Not recruiting

Phase: Phase 1

Date of First Enrollment: September 2025 ...