International Clinical Trial: Dose Exploration of Liposomal Bupivacaine Injection Combined with Bupivacaine for Postoperative Analgesia in Elderly Patients Undergoing Total Knee Arthroplasty

Geneva, June 22 -- International Clinical Trials Registry received information related to the study (ChiCTR2600126498) titled 'Dose Exploration of Liposomal Bupivacaine Injection Combined with Bupivacaine for Postoperative Analgesia in Elderly Patients Undergoing Total Knee Arthroplasty' on June 10.

Study Type: Interventional study

Study Design: Single arm

Primary Sponsor: Hebei Cangzhou Hospital of Integrated Traditional Chinese Medicine and Western Medicine

Condition: Knee Osteoarthritis

Intervention: Experimental Group:Ultrasound-guided adductor canal block with 5 mL mixture containing 0.665% liposomal bupivacaine (LB) plus 0.2% bupivacaine, with adaptive volume adjustment: the initial injection volume is 10 mL and the incremen...