Geneva, Oct. 21 -- International Clinical Trials Registry received information related to the study (NCT07209215) titled 'ctDNA-Informed Management of Early-Stage Rectal Cancer' on Sept. 30.

Study Type: Interventional

Study Design: Allocation: Non-Randomized. Intervention model: Parallel Assignment. Primary purpose: Treatment. Masking: None (Open Label).

Primary Sponsor: University of California, Davis

Condition: Rectal Adenocarcinoma Rectal Cancer Early-stage Rectal Cancer Locally Advanced Rectal Adenocarcinoma

Intervention: Drug: Signatera Genome ultra-sensitive ctDNA blood test + total neoadjuvant therapy (TNT)

Recruitment Status: Not recruiting

Phase: Phase 2

Date of First Enrollment: November 2025

Target Sample Size: 2...