International Clinical Trial: Comparison of the effects of different doses of liposomal bupivacaine on sciatic nerve block on foot and ankle function after total knee arthroplasty (TKA)

Geneva, Jan. 12 -- International Clinical Trials Registry received information related to the study (ChiCTR2500114859) titled 'Comparison of the effects of different doses of liposomal bupivacaine on sciatic nerve block on foot and ankle function after total knee arthroplasty (TKA)' on Dec. 18, 2025.

Study Type: Interventional study

Study Design: Parallel

Primary Sponsor: Foshan Fosun Chancheng Hospital

Condition: Osteoarthritis and end-stage knee disease

Intervention: Low-dose group:After undergoing total knee arthroplasty (TKA), the patient was transferred to the anesthesia recovery room for observation. Under ultrasound guidance, combined with a nerve stimulator, the "one-needle four-point method" for nerve block analgesia was ...