International Clinical Trial: Comparison of Prolonged and Intermittent Beta-Lactam Antibiotic Infusions in Critically Ill Children with Sepsis (BUILD)

Geneva, March 20 -- International Clinical Trials Registry received information related to the study (ACTRN12626000226303) titled 'Comparison of Prolonged and Intermittent Beta-Lactam Antibiotic Infusions in Critically Ill Children with Sepsis (BUILD)' on Feb. 24.

Study Type: Interventional

Study Design: Purpose: Treatment Allocation: Randomised controlled trial Masking: Open (masking not used) Assignment: Parallel Type of endpoint: Safety/efficacy

Primary Sponsor: The University of Queensland

Condition: Sepsis Sepsis Infection - Other infectious diseases

Intervention: Patients will be allocated 1:1:1 to one of the three treatment groups.

Arm 1 (Intervention 1), continuous infusion: Loading dose (calculated as per intermittent in...