International Clinical Trial: Clinical study on the safety and efficacy of 3D extracellular vesicles combined with sodium hyaluronate in the treatment of knee osteoarthritis

Geneva, Jan. 12 -- International Clinical Trials Registry received information related to the study (ChiCTR2500115601) titled 'Clinical study on the safety and efficacy of 3D extracellular vesicles combined with sodium hyaluronate in the treatment of knee osteoarthritis' on Dec. 29, 2025.

Study Type: Interventional study

Study Design: Parallel

Primary Sponsor: The Third Affiliated Hospital of Sun Yat-sen University (Sun Yat-sen University Liver Disease Hospital)

Condition: Degenerative arthritis of knee joint

Intervention: Low dose exosome treatment group:ARTZ(Sodium Hyaluronate Injection) 2.5ml (25mg)+5 x 10 ^ 9 particles of extracellular vesicles, injected into the knee joint cavity Control group:ARTZ(Sodium Hyaluronate Injectio...