Geneva, March 20 -- International Clinical Trials Registry received information related to the study (ChiCTR2600119211) titled 'Clinical research on esketamine for improving postoperative sleep quality in heart valve surgery patients' on Feb. 24.

Study Type: Interventional study

Study Design: Parallel

Primary Sponsor: Nanjing First Hospital

Condition: None

Intervention: The low-dose esketamine group (ED group):During the operation, 2.5 mg/ml low-dose esketamine (0.15 mg·kg-1·h-1) was pumped at a rate of 0.06 ml·kg-1·h-1 until the end of the surgery. The medium-dose esketamine group (Group E):During the operation, 5 mg/ml of the medium-dose esketamine (0.3 mg·kg-1·h-1) was pumped at a rate of 0.06 ml&#...