International Clinical Trial: An open-label, positive drug-controlled, parallel-group, multicenter phase II clinical trial on the efficacy, safety and pharmacokinetics of flonoltinib maleate tablet in patients with intermediate and high-risk myelofibrosis

Geneva, Jan. 12 -- International Clinical Trials Registry received information related to the study (ChiCTR2500115640) titled 'An open-label, positive drug-controlled, parallel-group, multicenter phase II clinical trial on the efficacy, safety and pharmacokinetics of flonoltinib maleate tablet in patients with intermediate and high-risk myelofibrosis' on Dec. 29, 2025.

Study Type: Interventional study

Study Design: Parallel

Primary Sponsor: Institute of Hematology, Chinese Academy of Medical Sciences / West China Hospital of Sichuan University

Condition: Myelofibrosis

Intervention: The low-dose test group:Flonoltinib Maleate Tablet 50mg, oral administration, once daily, given on an empty stomach. The high-dose test group:Flonoltin...