Geneva, Sept. 25 -- International Clinical Trials Registry received information related to the study (ChiCTR2600132504) titled 'A multi-Center, prospective, observational study of the disease burden of Hypoph' on Sept. 15.
Study Type: Observational study
Study Design:
Cohort study
Primary Sponsor: Peking Union Medical College Hospital
Condition:
Hypophosphatasia (HPP) is a rare inherited metabolic disorder caused by mutations in the ALPL gene, which leads to impaired mineralization of bones and teeth. This disease presents with highly heterogeneous clinical manifestations and imposes a substantial lifelong disease burden. Currently, most evidence on the disease burden of HPP is derived from Western populations, while prospective rea...