International Clinical Trial: A Comparison of the Efficacy of Novel G-Protein Biased µ-Opioid Receptor Agonists and Traditional Opioids in Chronic Postoperative Pain Following Thoracoscopic Surgery

Geneva, Jan. 12 -- International Clinical Trials Registry received information related to the study (ChiCTR2500115661) titled 'A Comparison of the Efficacy of Novel G-Protein Biased µ-Opioid Receptor Agonists and Traditional Opioids in Chronic Postoperative Pain Following Thoracoscopic Surgery' on Dec. 29, 2025.

Study Type: Interventional study

Study Design: Parallel

Primary Sponsor: Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital)

Condition: chronic post-surgical pain,CPSP

Intervention: Teglitide Group:A bolus dose of 0.75 mg tegileridine is diluted to 3 ml, and the postoperative IV-PCA pump is prepared with tegileridine at 0.075 mg/kg diluted to a total volume of 200 ml, with a PCA bol...