U.S., Nov. 6 -- ClinicalTrials.gov registry received information related to the study (NCT07919431) titled 'Use of cfDNA in Monitoring and Guiding Treatment for Cervical Cancer' on Nov. 01.
Brief Summary: This is a prospective, single-center, observational cohort study that plans to enroll 100 women aged 18 years or older with histologically confirmed cervical cancer who are scheduled to receive radical surgery, radiotherapy, or systemic therapy. The study aims to establish and validate a low-depth cfDNA fragmentomics approach-including tumor fraction, fragment length distribution, and copy number variation-together with cfHPV-DNA testing for monitoring recurrence risk and predicting treatment response. Serial blood samples (10 mL per coll...